By Roy Zent,Ambra Pozzi
Cancer was once idea to originate from changes in intercellular signaling that led to the transformation of cells, their out of control proliferation and metastasis. there's now an expanding physique of proof demonstrating that the encompassing matrix and cell-matrix interactions also are significant gamers during this approach. Cells adhere and obtain indications from a variety of extracellular matrices through transmembrane receptors, the simplest recognized of that are the heterodimeric glycoproteins, integrins.
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Cell-Extracellular Matrix Interactions in Cancer by Roy Zent,Ambra Pozzi